Sekyiwa Shakur is the only person who shared Tupac’s entire childhood with him, the moves, the poverty, their mother’s addiction. Today she heads the foundation Afeni Shakur set up after his death.
Growing up at Tupac’s side
Sekyiwa, known in the family as “Set,” was born in 1975, the daughter of Afeni Shakur and Mutulu Shakur. She was Tupac’s half-sister, four years younger. Through her father she is also the half-sister of Mopreme Shakur and his siblings.
The children grew up in Harlem and the Bronx. Their father was on the run from 1981 and in prison from 1986; their mother slid into crack addiction. In 1984 the family moved to Baltimore. When a boy from the neighborhood was shot dead there, Afeni sent the children to family friends in Marin County near San Francisco; according to the authorized biography, Sekyiwa was already living there when her mother and brother followed in 1988.
Brother and sister
Tupac and Set, as Afeni put it, were always trying to make each other proud. Vanity Fair described a scene from Tupac’s last weeks in 1997: Sekyiwa had enrolled in cosmetology classes so she could start a cosmetics line with Tupac’s fiancée Kidada Jones. Tupac went out to the car to tell her how proud he was of her. In those days mother and sister often stayed at his house in Calabasas for weeks, together with Sekyiwa’s children.
She has two children, Nzingha and Malik, who are named as Mutulu’s grandchildren in the family’s obituary for him. According to People, she had both while still in high school.
Work for the foundation
According to People, Sekyiwa later studied in Atlanta and worked as a program coordinator for “Teens on the Rise,” an HIV and teen pregnancy prevention program. The Tupac Amaru Shakur Foundation describes her as one of its original board members; she started out as student liaison and program coordinator before becoming its president.
Speaking for the family
Since the deaths of her mother in 2016 and her father in 2023, Sekyiwa has spoken for the family more often. When Tupac received a posthumous star on the Hollywood Walk of Fame on June 7, 2023, she accepted it. “Tupac knew deep down that he was always meant for something great,” she said, “and as his little sister, I had the privilege to watch that greatness unfold.” He had dreamed of that star ever since he first stepped onto the stage of the Apollo Theater at 13.
After Duane “Keffe D” Davis was arrested in September 2023, she wrote that this was “no doubt a pivotal moment,” but that she would reserve judgment until all the facts and legal proceedings were complete. On August 31, 2026, a Las Vegas jury found Davis guilty of murder; Sekyiwa was in the courtroom. Sentencing is set for October 13, 2026, and Davis has said he will appeal (as of October 2026).
Unconfirmed Claims
Other accounts mention a wedding on August 9, 2003, a guest appearance on Killa Tay’s album Snake Eyez and an interview on the Tupac: Resurrection DVD. These details could not be independently confirmed and are therefore not presented here as fact.